Dexamethasone Acetate Description

CAS Number:      1177-87-3

Purity:    ≥99%

Molecular Weight:     434.5

Molecular Formula:    C24H31FO6

Appearance:      Crystalline powder

Physical State:  Solid

Solubility:      Soluble in alcohol, DMSO (87 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), ethanol (20 mg/ml at 25 °C), and methanol.

Storage:   Store at 4° C

Melting Point:   225 °C (dec.)

Boiling Point:   579.39 °C at 760 mmHg (Predicted)

Density:   1.30 g/cm3 (Predicted)

Application:     A glucocorticoid

Description:

Dexamethasone Acetate is a glucocorticoid with anti-inflammatory properties. One accessible approach of action of the anti-inflammatory backdrop has been accurate by Dexamethasone Acetate inhibitiing upregulation of ICAM-1 (intercellular adherence molecule-1) in able animal mast cells. The admixture aswell displays anti mitotic action adjoin chemically adapted abrasion fibroblasts by awkward mitosis from entering the S-phase. Dexamethasone Acetate has aswell been bent to clearly abatement the amount of activated macrophages. In addition, Dexamethasone Acetate has been empiric to decidedly abatement mRNA levels of TPH2 (tryptophan hydroxylase-2) in the raphe nuclei of C57/Bl6 mice.