Muscimol Description

CAS Number: 2763-96-4

Purity: ≥98%

Molecular Weight:   114.10

Molecular Formula:  C4H6N2O2

Solubility: Soluble in water (10 mg/ml), methanol, ethanol, 0.05 M HCl (20 mg/ml), DMSO (sparingly soluble), DMF (sparingly soluble), and PBS (pH 7.2) (10 mg/ml).

Storage:    Store at 4° C

Melting Point:  176° C (dec.)

Boiling Point:  325° C at 760 mmHg (Predicted)

Density:    1.29 g/cm3 (Predicted)

Application:    A potent and specific GABAA receptor agonist/GABA analog

Description:

Muscimol is a by itself occurring alkaloid abandoned from assorted Amanita mushrooms, anatomic as a almighty and careful agonist of the GABAA receptor. The anatomy of Muscimol places the bounden functionalities (amine, hydroxyl) in a spatial adjustment about identical to that of GABA, acceptance acceptance of Muscimol at the awful specific GABAA bounden site. Muscimol has been broadly active for this agonist action in studies acid the consistent furnishings of GABAA stimulation.