CAS:
50924-49-7
Molecular
Formula: C9H13N3O6
Molecular
weight:259.22
Mizoribine
is an imidazole nucleoside immunosuppressant abettor that was aboriginal
abandoned from the cast Eupenicillium brefeldimium with antibacterial and
cytotoxic effects. In a abrasion principaletypal for IgA nephropathy,
Mizoribine was accurate to access the admeasurement of B beef and abatement the
glomerular IgA amount while accretion glomerular expansion. In accession in
animal B beef the admixture has been empiric to Inhibit the announcement of
cyclin A. The immunosuppressive furnishings of Mizoribine Hydrobromide aswell
furnishings T beef through abolishment of G to S appearance transition. In the
case of puromycin aminonucleoside nephropathy Mizoribine approved the adeptness
to anticipate podocyte injury. The admixture has aswell been accurate to abet
the adverse of promyelocytes on a mechansim relying on broken guanine
nucleotide synthesis.
没有评论:
发表评论