Enteropeptidase Applications

Enteropeptidase (also alleged enterokinase) is an agitator produced by beef of the duodenum and complex in beastly and beastly digestion. It is buried from abdominal glands (the crypts of Lieberkühn) afterward the access of ingested aliment casual from the stomach. Enteropeptidase converts trypsinogen (a zymogen) into its alive anatomy trypsin, consistent in the consecutive activation of pancreatic digestive enzymes.Absence of enteropeptidase after-effects in abdominal assimilation impairment.

Enteropeptidase is a serine protease (EC 3.4.21.9) consisting of a disulfide-linked heavy-chain of 82-140 kDa that anchors enterokinase in the abdominal besom bound film and a light-chain of 35–62 kDa that contains the catalytic subunit. Enteropeptidase is a allotment of the chymotrypsin-clan of serine proteases, and is structurally agnate to these proteins.

Enteropeptidase's specificity makes it an ideal apparatus in biochemical applications; a admixture protein absolute a C-terminal affection tag (such as poly-His) affiliated by this arrangement can be broken by enteropeptidase to access the ambition protein afterward protein purification. On the converse, the N-terminal pro-sequence of proteases that have to be broken above-mentioned to activation can be mutated to accredit activation with enteropeptidase.

more about:cosmetics-add.com/Cosmetic-Ingredients/Whitening-Skin-Care/Enterokinase-Enteropeptidase/