About Jo-1 ELISA Kit

　　Product name:   Jo-1 ELISA Kit　　Category Name:   Autoimmune Disease kits
　　ELISA method:  Enzyme Linked Immunosorbent Assay
　　Detection Range:   Qualitative elisa assay- Positive, Negative and Cut-off
　　Specificity:  99%
　　Sensitivity:  100%
　　Total Time:  60 min
　　Shelf Life:  12 months
　　Description:　　The Diagnostic Automation Jo-1 ELISA kit is intended for the detection and semi-quantization of antibodies to Jo-1 in human sera. The assay is to be used to detect antibodies in a single serum specimen. The results of the assay are to be used as an aid to the diagnosis of autoimmune disease. This is for in vitro diagnostic use.
　　Circulating antibodies to intra-cellular structures especially to nuclear antigens represent a characteristic feature of Jo-1 ELISA systemic autoimmune diseases. One of those antigens, Jo-1 (Aminoacyl-tRNA Synthetase), was first described in the serum of a myositis patient. A large number of patients with anti-synthetase syndrome suffer from interstitial lung disease, Raynaud’s Phenomenon, mechanic’s hands and arthritis. Anti-Jo-1 antibodies are strongly associated with isolated anti-Ro52 antibodies.
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