Cefixime, an antibiotic, is a
third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is
awful abiding in the attendance of beta-lactamase enzymes. As a result,
abounding bacilli aggressive to penicillins and some cephalosporins due to the
attendance of beta-lactamases, may be affected to cefixime. The antibacterial
aftereffect of cefixime after-effects from inhibition of mucopeptide amalgam in
the bacterial corpuscle wall.
For use in the analysis of the afterward
infections if acquired by affected strains of the appointed microorganisms:
(1) apprehensible urinary amplitude
infections acquired by Escherichia coli and Proteus mirabilis,
(2) otitis media acquired by Haemophilus
influenzae (beta-lactamase absolute and abrogating strains), Moraxella
catarrhalis (most of which are beta-lactamase positive), and S. pyogenes,
(3) pharyngitis and tonsillitis acquired by
S. pyogenes,
(4) astute bronchitis and astute
exacerbations of abiding bronchitis acquired by Streptococcus pneumoniae and
Haemophilus influenzae (beta-lactamase absolute and abrogating strains)
(5) apprehensible gonorrhea
(cervical/urethral) acquired by Neisseria gonorrhoeae (penicillinase- and
non-penicillinase-producing strains).
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