Description of Hyoscyamine

Hyoscyamine is the 3(S)-endo isomer of atropine.

Hyoscyamine is a belladonna alkaloid acquired and the levorotatory anatomy of racemic atropine abandoned from the plants Hyoscyamus niger or Atropa belladonna, which exhibits anticholinergic activity. Hyoscyamine functions as a non-selective, aggressive adversary of muscarinic receptors, thereby inhibiting the parasympathetic activities of acetylcholine on the salivary, bronchial, and diaphoresis glands, as able-bodied as the eye, heart, bladder, and gastrointestinal tract. These inhibitory furnishings could cause a abatement in saliva, bronchial mucus, belly juices, and sweat. Furthermore, its inhibitory activity on bland beef prevents float abbreviating and decreases gastrointestinal motility.

Hyoscyamine competes agreeably with acetylcholine for bounden at muscarinic receptors in the salivary, bronchial, and diaphoresis glands as able-bodied as in the eye, heart, and gastrointestinal tract. The accomplishments of hyoscyamine aftereffect in a abridgement in salivary, bronchial, belly and diaphoresis gland secretions, mydriasis, cycloplegia, change in affection rate, abbreviating of the float detrusor beef and of the gastrointestinal bland muscle, and decreased gastrointestinal motility.