Phytic Acid Biological and physiological roles

Although boxy for abounding animals, phytic acid and its metabolites as they action in seeds and grains accept several important roles for the bulb plant.

Most notably, phytic acid functions as a phosphorus store, as an activity store, as a antecedent of cations and as a antecedent of myoinositol (a corpuscle bank precursor). Phytic acid is the arch accumulator anatomy of phosphorus in bulb seeds.

In beastly cells, myoinositol polyphosphates are ubiquitous, and phytic acid (myoinositol hexakisphosphate) is the a lot of abundant, with its absorption alignment from 10 to 100 uM in beastly cells, depending on corpuscle blazon and adorning stage.

This admixture is not acquired from the beastly diet, but accept to be actinic central the corpuscle from phosphate and inositol (which in about-face is produced from glucose, usually in the kidneys). The alternation of intracellular phytic acid with specific intracellular proteins has been advised in vitro, and these interactions accept been begin to aftereffect in the inhibition or potentiation of the physiological activities of those proteins. The best affirmation from these studies suggests an intracellular role for phytic acid as a cofactor in DNA adjustment by nonhomologous end-joining. Other studies application aggrandize mutants accept aswell appropriate intracellular phytic acid may be complex in mRNA consign from the basis to the cytosol.There are still above gaps in the compassionate of this molecule, and the exact pathways of phytic acid and lower inositol phosphate metabolism are still unknown. As such, the exact physiological roles of intracellular phytic acid are still a amount of debate.