Ceftiofur sodium is a third bearing cephalosporin antibacterial able adjoin gram-positive
and gram-negative bacteria. Although ceftiofur is aggressive to β-lactamase
degradation, there are several strains of E. coli accepted to be artless by
this antibiotic. It is acrid in aqueous solution.
Ceftiofur
Sodium is the sodium alkali anatomy of ceftiofur, a semisynthetic,
beta-lactamase-stable, broad-spectrum, third-generation cephalosporin with
antibacterial activity. Ceftiofur binds to and inactivates penicillin-binding
proteins (PBPs) amid on the close film of the bacterial corpuscle wall. PBPs
are enzymes complex in the terminal stages of accumulating the bacterial
corpuscle bank and in about-face the corpuscle bank during advance and
division. Inactivation of PBPs interferes with the cross-linkage of
peptidoglycan chains all-important for bacterial corpuscle bank backbone and
rigidity. This after-effects in the abrasion of the bacterial corpuscle bank
and causes corpuscle lysis.

没有评论:
发表评论