11/28/2017

Where to buy Daunorubicin Hydrochloride?


CAS: 23541-50-6
Molecular Formula: C27H29NO10.HCl
Molecular Weight: 563.99
Daunorubicin Hydrochloride is rapidly and broadly broadcast in tissues, with accomplished levels in the spleen, kidneys, liver, lungs, and heart. The biologic binds to abounding cellular components, decidedly nucleic acids. There is no affirmation that Daunorubicin Hydrochloride crosses the blood-brain barrier, but the biologic calledly crosses the placenta.
Daunorubicin Hydrochloride is abundantly metabolized in the alarmist and added tissues, mainly by cytoplasmic aldo-keto reductases, bearing daunorubicinol, the above metabolite which has antineoplastic activity. Approximately 40% of the biologic in the blood is present as daunorubicinol aural 30 account and 60% in 4 hours afterwards a dosage of daunorubicin. Further metabolism via abridgement break of the glycosidic bond, 4-O demethylation, and alliance with both sulfate and glucuronide accept been demonstrated. Simple glycosidic break of daunorubicin or daunorubicinol is not a cogent metabolic alleyway in man. Twenty-five percent of an administered dosage of Daunorubicin Hydrochloride is alone in an active anatomy by urinary elimination and an estimated 40% by biliary excretion.

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