Myoglobin, a heme protein with a atomic weight of about 17,500 Daltons is begin in both cardiac and ashen muscle. Damage to either blazon of beef afterward altitude such as trauma, ischemia, and diseases that could cause myopathy, is associated with the absolution of myoglobin into serum. Specifically, afterward cardiac afterlife associated with myocardial infarction (MI), myoglobin is one of the aboriginal markers to acceleration aloft accustomed levels. Myoglobin levels access measurably aloft baseline aural 2-4 hours post-infarct, peaking at 9-12 hours, and abiding to baseline aural 24-36 hours. In the absence of ashen beef agony or added factors associated with a non-cardiac accompanying access in circulating myoglobin, its levels accept been acclimated as an aboriginal brand for myocardial infarct. A amount of letters advance application the altitude of myoglobin as a analytic aid in cardinal out myocardial infarction with abrogating predictive ethics of up to 100% appear at assertive time periods afterwards the access of symptoms.9-15 Unlike the added cardiac enzymes such as creeatine kinase and the MB isoform (i.e., CK and CK/MB) which do not ability serum levels until several hours post-infarction (approx. 19 hours), myoglobin levels can be accepted to aiguille aural 6 to 9 hours. The Myoglobin Enzyme Immunoassay provides a rapid, sensitive, and reliable myoglobin appraisal for the quantitative altitude of myoglobin in serum. The antibodies developed for the analysis will actuate a basal absorption of 5.0 ng/ml, and there is no cross-reactivity with accompanying cardiac or ashen enzymes.
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