The following steps show you how to prevent Nocardia infection.
1, using trimethoprim-sulfamethoxazole (TMP-SMX) as prophylaxis in patients with AIDS, chronic granulomatous disease and other diseases immunocompromising. This is usually for the purposes of prevention of Pneumocystis pneumonia. Be aware that this therapy can reduce the symptoms of Nocardia and complicate a diagnosis.
2, use of chronic suppressive therapy with TMP-SMX to prevent recurrence of Nocardia infection. Recurrence of infection is the most common complication of nocardiosis so it is very important to complete the entire treatment. A CD4 cell count below 200 cells / ml should decrease the incidence of nocardiosis in these patients.
3rd Treat mild cases for at least six weeks, while severe infections may need to be treated for one year. All treatment should be continued until at least one month after all signs of infection have subsided.
4, Nocardia expect to be at least partially resistant to antibiotics during prolonged treatment.
5, Consider the use of corticosteroids in the prevention of pulmonary nocardiosis. AIDS drugs in the smallest doses and for the shortest time that is effective should be used.
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