The β-defensins are small, cysteine-rich, cationic peptides expressed throughout the epithelia of many organs. Expression of these defensin genes is regulated in response to infection and inflammation. β-defensins play important roles along with α-defensins in the human primary defense system against infection. They have been reported to link innate and adaptive immunity by attracting immature dendritic cells and memory T-cells. The antimicrobial, antiviral, and immunomodulatory properties of β-defensins increase resistance to infection. Due to their unique mechanism of action, β-defensins are expected to be ideal therapeutic agents as peptide antibiotics, mitigating the problem of acquired resistance.
more about:buy β-Defensin-2 (human recombinant)
没有评论:
发表评论